Melanotan 2 (MT-2) is a synthetic peptide and analogue of alpha-melanocyte-stimulating hormone. MT-2 has a shorter amino acid sequence than melanotan 1 (afamelanotide), and is believed to have a stronger effect on melanocortin receptors 3 and 4, involved in penile erection and appetite suppression.
Like MT-1, MT-2 is commonly used as a sunless tanning agent and to stimulate sexual arousal, and is also known to reduce hunger, alleviate compulsive/addictive behavior, and improve body composition.
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Very briefly, Melanotan is a synthetic peptide that has a chemical structure very similar to a peptide hormone that is naturally produced in, and secreted by, the pituitary gland: alpha-melanocyte-stimulating hormone (α-MSH) [1].
This peptide, α-MSH, has several roles and functions. It binds to a particular family of receptors called melanocortin receptors and helps regulate a number of bodily functions [2].
For instance, one of the melanocortin receptors, MC-1R, upregulates the production of melanin in the body. Melanin is the pigment substance that makes the skin darker and is produced in specialized cells throughout the skin called melanocytes. Increasing the amount of melanin in the skin increases protection against sun damage.
There are a number of additional effects that Melanotan has via the melanocortin receptors. For example, the third melanocortin receptor, MC-3R, is involved in appetite regulation. That’s why Melanotan has been found to have the effect of regulating (and decreasing) appetite.
Also, the fourth melanocortin receptor, MC-4R, is involved in the regulation of sexual activity, which is why Melanotan 2 has been found to have a significant effect on increasing libido and improving erectile function. So Melanotan is a pretty versatile peptide.
There are two types of Melanotan – Melanotan 1 and Melanotan 2 – otherwise known as MT-1 and MT-2. Let’s look at the main similarities and differences between these two peptides.
There are two types of Melanotan: type 1 and type 2. They are often referred to as Melanotan I and Melanotan II, or MT-1 and MT-2, respectively.
What is the difference between MT-1 and MT-2?
Basically, they differ in their chemical structure. MT-1 is a straight, longer peptide whereas MT-2 is a shorter, circular peptide. That difference in shape and structure means that they bind differently to the melanocortin receptors and have slightly different effects.
Past research has shown that Melanotan 1 can:
As Melanotan 1 has a shorter half-life than Melanotan II, its effects don’t last as long. It is typically more expensive and less popular among researchers than Melanotan II.
Past research has shown that Melanotan 2 can:
As Melanotan 2 has a longer half-life than Melanotan I, its effects last longer, It is not available as a prescription medication and is typically less expensive than Melanotan I when purchased as a research chemical. This means that MT-1 is generally more popular than Melanotan II among researchers.
In the following section, we’ll look at some of the benefits of Melanotan 2.
Past research involving Melanotan has found that this research chemical has the following effects:
Together these Melanotan benefits are quite impressive. They’re the reason why researchers worldwide are actively investigating this research chemical. In the following section, we’ll explore where Melanotan can be purchased by researchers.
So where should researchers buy Melanotan?
MT-1, which is sold under the trade name “Scenesse” (and which is also called by its generic name “Afamelanotide”) is available as a prescription medication in the US, Europe, and several other countries for people with a diagnosis of erythropoietic protoporphyria.
Erythropoietic protoporphyria is a condition in which an individual has an extreme sensitivity to sunlight. For these people, normal sun exposure can be painful. Afamelanotide (Melanotan 1) helps these people increase the melanin in their skin, which reduces the pain they feel from sunlight.
Therefore, individuals who have been diagnosed with erythropoietic protoporphyria may be able to buy Melanotan with a prescription.
Melanotan can also be purchased online by prescription-holders and is often substantially less expensive than the brand-name products sold in pharmacies.
Researchers can also purchase Melanotan online as a research chemical for the purpose of conducting experiments.
We’ll go into detail about the best place to buy Melanotan online a bit later on in this article. But the burning question is…
In most countries, yes.
First, of course, laws differ by country, so researchers are advised to check local laws and regulations before placing an order.
But, in most places, Melanotan 2 can be legally purchased by researchers for research purposes. Researchers planning to use Melanotan in research will usually find that it’s absolutely legal in many countries to do just that.
However, it’s typically not legal for local stores to sell Melanotan for research. That’s why researchers probably won’t find it at local supplement stores. Those looking to try out Melanotan will have to head online.
It’s pretty easy these days for researchers to get peptide orders shipped to the USA. But what about researchers located internationally? Can they buy Melanotan 2 abroad?
Well, it depends on where the researcher is located.
Many research peptides vendors ship internationally to over 170 countries, including Canada, the UK, and most of Europe.
When working with Melanotan 2, researchers must have access to the right tools.
For both safety and efficacy, the lab should be equipped with sterile vials and bacteriostatic water, among other essential supplies.
While many researchers struggle to gather all these items in a timely and affordable manner, this is essential prior to conducting research.
Researchers will want to gather items like these listed below and more:
Researchers actively considering Melanotan research may be trying to decide whether it’s worth the risk. Hopefully, this guide has allayed any fears that researchers may have and helped them find a reputable vendor that can supply research-grade Melanotan for experimentation.
Researchers interested in exploring Melanotan 2 and its benefits and side effects are encouraged to consult the guidelines above when choosing a vendor. This will reduce the risk of losing money and increase the chances of finding pure Melanotan for sale.
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